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Hinokitiol

Chemical Structure : Hinokitiol

CAS No.: 499-44-5

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Hinokitiol (4-Isopropyltropolone;β-Thujaplicin)

Catalog No.: PC-62331Not For Human Use, Lab Use Only.

Hinokitiol (4-Isopropyltropolone.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Hinokitiol (4-Isopropyltropolone;β-Thujaplicin) is a tropolone-related natural compound that can induces apoptosis and cell cycle arrest, exhibits anti-inflammatory and anti-tumor activities; inhibits the proliferation of Chlamydia trachomatis with MIC of 32 ug/mL; also can harness such gradients to restore iron transport into, within, and/or out of cells.

Physicochemical Properties

M.Wt 164.204
Formula C10H12O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one

References

1. Yamano H, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2519-21.

2. Seo JS, et al. BMC Cell Biol. 2017 Feb 27;18(1):14.

3. Grillo AS, et al. Science. 2017 May 12;356(6338):608-616.

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