| Cat. No. |
Product Name |
Information |
| PC-47089 |
Tpz-1
PCD inducer
|
Tpz-1 is a unique cytotoxic compound that elicits potent and selective programmed cell death in human blood, breast, colon, and cervical cancer cell lines, interferes with components of signaling pathways and the cytoskeleton that are important to cell shape, internal organization, growth, and division. |
| PC-73048 |
Leusin-1
ALL G2 phase inhibitor inhibitor
|
Leusin-1 (Leukemia specific inhibitor 1) is a cell cycle phase specific inhibitor that specifically arrest leukemia cells during G2-phase and triggers an apoptotic cell death (CCRF-CEM IC50= 2.66 uM and TOM1 IC50= 0.877 uM). |
| PC-72413 |
WEHI-7326
Mitotic inhibitor
|
WEHI-7326 (WEHI 7326) is a specific mitotic inhibitor and potential anticancer agent, causes cell cycle arrest in G2/M, cell death in vitro (MDA-MB-231 IC50=24.4 nM), and displays efficacious anti-tumor activity in vivo. |
| PC-36025 |
CCI-007
Apoptosis inducer
|
CCI-007 (CCI 007) is a selective inhibitor of MLL-r, CALM-AF10 and SET-NUP214 leukemia with IC50 of 3.5 uM against MLL-r leukemia cell line PER-485. |
| PC-63230 |
NSC 745887
|
NSC 745887 is a small molecule that effectively inhibits the proliferation of various cancers by trapping DNA-topoisomerase cleavage, shows anticancer effects against human GBM cells via suppressing DcR3-associated signaling pathways. |
| PC-62586 |
NecroX-7
|
NecroX-7 is a small molecule necrosis modulator and potent antioxidant molecule, which can be bound to some types of radicals and especially NAPQI. |
| PC-42276 |
JPH203
LAT1 inhibitor
|
Nanvuranlat (JPH203, KYT-0353) is a potent, selective L-type amino acid transporter 1 (LAT1, SLC7A5) inhibitor with IC50 of 60 nM (leucine uptake inhibition), but not LAT2. |
| PC-22100 |
VDX-111
|
VDX-111 (AMPI-109) is a selectively active agent against TNBC cell lines, inhibits proliferation and induces apoptosis of multiple TNBC subtype cell lines with IC50 of 100 nM. |
| PC-22058 |
UM4118
Copper ionophore, Cuproptosis inducer
|
UM4118 is a potent, specific, and nongenotoxic molecule that acts as a copper ionophore, initiates a mitochondrial-based noncanonical form of cell death known as cuproptosis (IC50=40 nM, OCI-AML5 cells), disrupts intracellular metal homeostasis. |
| PC-21768 |
Raptinal
Apoptosis inducer
|
Raptinal is a small molecule rapid apoptosis inducer, initiates intrinsic pathway caspase-dependent apoptosis in multiple cell lines, also inhibits the activity of caspase-activated Pannexin 1 (PANX1). |
| PC-21095 |
EGCG
Anticancer
|
EGCG (Epigallocatechin-3-gallate) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis, inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity. |
| PC-20272 |
ANP0903
|
ANP0903 is an analog of HIV-1 protease inhibitor darunavir, induces cytotoxicity in hepatocellular carcinoma cell lines, triggers apoptosis by enhancing ER stress. |
