| Cat. No. |
Product Name |
Information |
| PC-38741 |
WZY-321
XAF1 modulator
|
WZY-321 a small molecule glioma cell apoptosis inducer, binds to XAF1 3-UTR and decreases XAF1 (X-linked inhibitor of apoptosis-associated factor 1) mRNA levels. |
| PC-38723 |
Devimistat
KGDH inhibitor
|
CPI-613 (Devimistat) is an antimitochondrial metabolism agent that specifically induces inactivating phosphorylation of tumor cell PDH via stimulation of PDKs 1 to 4, inhibits KGDH function strongly and rapidly, selectively in tumor cells. |
| PC-35324 |
Flavokawain B
|
Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression. |
| PC-43430 |
Silvestrol
|
Silvestrol is a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in cancer cells through the mitochondrial/apoptosome pathway. |
| PC-43429 |
Silvestrol aglycone
|
Silvestrol is a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in cancer cells through the mitochondrial/apoptosome pathway. |
| PC-42374 |
Iberin
|
Iberin is an isothiocyanate compound from horseradish that exhibits anticancer activity, a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa, and significantly induces Nrf2 nuclear translocation in NIH3T3 fibroblasts. |
| PC-42855 |
Elesclomol
|
Elesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells. |
| PC-62587 |
Necrox-5 methanesulfonate
|
NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter. |
| PC-62441 |
Carubicin
|
Carubicin (Carminomycin) is an apoptosis inducer that targets the Golgi complex, induces apoptosis in CCRCC cells by a mechanism independent of p53 or HIF2, and induces cleavage of the Golgi protein p115 and the translocation of its C-terminal fragment to the nucleus.. |
| PC-62440 |
GUT-70
|
GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation, viability through G1 cell cycle arrest and increases apoptosis. |
| PC-62331 |
Hinokitiol
|
Hinokitiol (4-Isopropyltropolone. |
| PC-61309 |
Imexon
|
A 2-cyanoaziridine derivative with antitumor activity in some types of cancer, including pancreatic, lung, breast, prostate, melanoma, and multiple myeloma. |
