| Cat. No. |
Product Name |
Information |
| PC-22902 |
Darinaparsin
Apoptosis inducer
|
Darinaparsin (ZIO-101) is a novel arsenical apoptosis inducer, induces apoptosis and oxidative stress to a greater extent than As(2)O(3), within c-Jun NH(2)-terminal kinase-dependent. |
| PC-22100 |
VDX-111
|
VDX-111 (AMPI-109) is a selectively active agent against TNBC cell lines, inhibits proliferation and induces apoptosis of multiple TNBC subtype cell lines with IC50 of 100 nM. |
| PC-22058 |
UM4118
Copper ionophore, Cuproptosis inducer
|
UM4118 is a potent, specific, and nongenotoxic molecule that acts as a copper ionophore, initiates a mitochondrial-based noncanonical form of cell death known as cuproptosis (IC50=40 nM, OCI-AML5 cells), disrupts intracellular metal homeostasis. |
| PC-21768 |
Raptinal
Apoptosis inducer
|
Raptinal is a small molecule rapid apoptosis inducer, initiates intrinsic pathway caspase-dependent apoptosis in multiple cell lines, also inhibits the activity of caspase-activated Pannexin 1 (PANX1). |
| PC-35324 |
Flavokawain B
|
Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression. |
| PC-43429 |
Silvestrol aglycone
|
Silvestrol is a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in cancer cells through the mitochondrial/apoptosome pathway. |
| PC-42374 |
Iberin
|
Iberin is an isothiocyanate compound from horseradish that exhibits anticancer activity, a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa, and significantly induces Nrf2 nuclear translocation in NIH3T3 fibroblasts. |
| PC-42855 |
Elesclomol
|
Elesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells. |
| PC-62587 |
Necrox-5 methanesulfonate
|
NecroX-5 is a novel necroptosis inhibitor that reduces mitochondrial oxidative stress, prevents hypoxia/reoxygenation injury by inhibiting the mitochondrial calcium uniporter. |
| PC-62441 |
Carubicin
|
Carubicin (Carminomycin) is an apoptosis inducer that targets the Golgi complex, induces apoptosis in CCRCC cells by a mechanism independent of p53 or HIF2, and induces cleavage of the Golgi protein p115 and the translocation of its C-terminal fragment to the nucleus.. |
| PC-62440 |
GUT-70
|
GUT-70 is a tricyclic coumarin derived from Calophyllum brasiliense, markedly reduces cell proliferation, viability through G1 cell cycle arrest and increases apoptosis. |
| PC-62331 |
Hinokitiol
|
Hinokitiol (4-Isopropyltropolone. |
