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Chemical Structure : VDX-111
Catalog No.: PC-22100Not For Human Use, Lab Use Only.
VDX-111 (AMPI-109) is a selectively active agent against TNBC cell lines, inhibits proliferation and induces apoptosis of multiple TNBC subtype cell lines with IC50 of 100 nM.
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VDX-111 (AMPI-109) is a selectively active agent against TNBC cell lines, inhibits proliferation and induces apoptosis of multiple TNBC subtype cell lines with IC50 of 100 nM.
VDX-111 (AMPI-109) also inhibits the growth of a panel of ovarian cancer cell lines, focusing on BRCA wild-type lines.
VDX-111 (AMPI-109) causes a dose-dependent loss of cell viability across ovarian cancer cell lines.
VDX-111 (AMPI-109) inhibits tumor growth in patient-derived xenograft and syngeneic murine models.
| M.Wt | 537.57 | |
| Formula | C29H45BrO4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Hamid H Gari, et al. Oncotarget. 2016 Mar 29;7(13):15757-71.
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