Catalog No.: PC-42374Not For Human Use, Lab Use Only.
Iberin is an isothiocyanate compound from horseradish that exhibits anticancer activity, a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa, and significantly induces Nrf2 nuclear translocation in NIH3T3 fibroblasts.
Iberin is an isothiocyanate compound from horseradish that exhibits anticancer activity, a quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa, and significantly induces Nrf2 nuclear translocation in NIH3T3 fibroblasts; induces cell cycle arrest and apoptosis in human neuroblastoma cells associated with inhibition of expression of Cdk2, Cdk4, and Cdk6 proteins.
Physicochemical Properties
M.Wt
163.26106
Formula
C5H9NOS2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
Ethanol: 10 mg/mL
Chemical Name/SMILES
Propane, 1-isothiocyanato-3-(methylsulfinyl)-
References
1. Jadhav U, et al. Int J Mol Med. 2007 Mar;19(3):353-61.
2. Jadhav U, et al. J Pharmacol Sci. 2007 Feb;103(2):247-51.
3. Jakobsen TH, et al. Appl Environ Microbiol. 2012 Apr;78(7):2410-21.
4. Tan SY, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6648-59.
