Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : WZY-321
Catalog No.: PC-38741Not For Human Use, Lab Use Only.
WZY-321 a small molecule glioma cell apoptosis inducer, binds to XAF1 3-UTR and decreases XAF1 (X-linked inhibitor of apoptosis-associated factor 1) mRNA levels.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
WZY-321 a small molecule glioma cell apoptosis inducer, binds to XAF1 3-UTR and decreases XAF1 (X-linked inhibitor of apoptosis-associated factor 1) mRNA levels.
WZY-321 increased XAF1 expression in glioma cells, and up-regulated XAF1 resulted in glioma cell apoptosis.
WZY-321 also decreased miR-873 expression and increased lncRNA MTM expression in glioma cells, and down-regulated miR-873 or up-regulated MTM lead to glioma cell apoptosis.
| M.Wt | 341.747 | |
| Formula | C18H12ClNO4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Guan Sun, et al. J Cancer. 2022 Apr 18;13(7):2312-2321.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
