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Chemical Structure : Hsp90α-IN-12h
Catalog No.: PC-72570Not For Human Use, Lab Use Only.
Hsp90α-IN-12h is the first Hsp90α-selective inhibitor with IC50 of 460 nM, exhibit 48-fold selectivity versus other Hsp90 isoforms.
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Hsp90α-IN-12h is the first Hsp90α-selective inhibitor with IC50 of 460 nM, exhibit 48-fold selectivity versus other Hsp90 isoforms.
In NCI-H522 cells, Hsp90a-dependent substrates are readily degraded in the presence of Hsp90a-selective inhibitor.
| M.Wt | 375.486 | |
| Formula | C23H21NO2S | |
| Appearance | Solid | |
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1. Sanket J Mishra, et al. Angew Chem Int Ed Engl. 2021 May 3;60(19):10547-10551.
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