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Hydralazine

Chemical Structure : Hydralazine

CAS No.: 86-54-4

Hydralazine

Catalog No.: PC-28367Not For Human Use, Lab Use Only.

Hydralazine is an orally active, blood-brain barrier-permeable DNA methyltransferase (DNMT) inhibitor, shows vasodilatory, arterial smooth muscle relaxant and hypotensive activities, also shows neuroprotective and anti-inflammatory properties.

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Biological Activity

Hydralazine is an orally active, blood-brain barrier-permeable DNA methyltransferase (DNMT) inhibitor, shows vasodilatory, arterial smooth muscle relaxant and hypotensive activities, also shows neuroprotective and anti-inflammatory properties.

Physicochemical Properties

M.Wt 160.18
Formula C8H8N4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Hydrazinylphthalazine

References

1. Leiro JM, et al. Int Immunopharmacol. 2004;4(2):163-177.

2. Segura-Pacheco B, et al. J Transl Med. 2006 Aug 7;4:32.

3. Singh N, et al. ChemMedChem. 2009 May;4(5):792-9.

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