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Hymeglusin

Chemical Structure : Hymeglusin

CAS No.: 29066-42-0

Hymeglusin

Catalog No.: PC-22682Not For Human Use, Lab Use Only.

Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity.

Physicochemical Properties

M.Wt 324.42
Formula C18H28O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,4-Undecadienoic acid, 11-[(2R,3R)-3-(hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-, (2E,4E,7R)-

References

1. Cheng Zhou, et al. Blood Sci. 2024 Jul 10;6(3):e00192.

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