Hymeglusin

Chemical Structure : Hymeglusin

Catalog No.: PC-22682Not For Human Use, Lab Use Only.

Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity.

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Biological Activity

Hymeglusin is a fungal β-lactone antibiotic and HMG-CoA synthase 1 (HMGCS1) inhibitor with IC50 of 0.12 uM, suppresses the growth of AML cells and enhances their chemosensitivity.

Physicochemical Properties

M.Wt	324.42
Formula	C18H28O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,4-Undecadienoic acid, 11-[(2R,3R)-3-(hydroxymethyl)-4-oxo-2-oxetanyl]-3,5,7-trimethyl-, (2E,4E,7R)-

References

1. Cheng Zhou, et al. Blood Sci. 2024 Jul 10;6(3):e00192.

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Hymeglusin

Biological Activity

Physicochemical Properties

References

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