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Chemical Structure : I-BET469
Catalog No.: PC-22528Not For Human Use, Lab Use Only.
I-BET469 is a potent, selective pan-BET bromodomain inhibitor with pIC50 of 7.9 for BRD4 BD1, >5000-fold selective over BAZ2A.
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I-BET469 is a potent, selective pan-BET bromodomain inhibitor with pIC50 of 7.9 for BRD4 BD1, >5000-fold selective over BAZ2A.
I-BET469 inhibits human whole blood MCP-1 with an pIC50 value of 7.6, inhibits LPS-stimulated hWB IL-6 with pIC50 of 7.7.
| M.Wt | 426.52 | |
| Formula | C23H30N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Christopher R Wellaway, et al. J Med Chem. 2020 Jan 23;63(2):714-746.
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