I1421 | CFTR potentiator | Probechem Biochemicals

Chemical Structure : I1421

Catalog No.: PC-22440Not For Human Use, Lab Use Only.

I1421 is a potent, small molecule CFTR potentiator with EC50 of 64 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

I1421 is a potent, small molecule CFTR potentiator with EC50 of 64 nM.

M.Wt	343.36
Formula	C18H18FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-(3-amino-6-(hydroxymethyl)-1H-indazol-1-yl)-3-(4-fluorophenoxy)-2-methylpropan-1-one

1. Liu F, et al. Cell. 2024 May 23:S0092-8674(24)00472-0.