Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : IAXO-102
CAS No.: 1115270-63-7
Catalog No.: PC-63208Not For Human Use, Lab Use Only.
IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $328 | In stock | |
| 25 mg | $528 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
IAXO-102 is a novel selective TLR4 antagonist, negatively regulates non-hematopoietic TLR4 signalling and inhibits experimental AAA development.
IAXO-102 inhibits MAPK and p65 NF-kB phosphorylation associated with down regulation of the expression of TLR4 and TLR4 dependent proinflammatory proteins.
IAXO-102 decreases Angiotensin II-induced aortic expansion, rupture and incidence of abdominal aortic aneurysm (AAA).
| M.Wt | 585.955 | |
| Formula | C35H71NO5 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Methyl 6-amino-6-deoxy-2,3-di-O-tetradecyl-a-D-glucopyranoside |
|
1. Huggins C, et al. Atherosclerosis. 2015 Oct;242(2):563-70.
2. Kawakita F, et al. Mol Neurobiol. 2017 Oct;54(8):6624-6633.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
