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Chemical Structure : ICMT inhibitor C75
Catalog No.: PC-49240Not For Human Use, Lab Use Only.
ICMT inhibitor C75 is a potent, specific and cell-permeable inhibitor of the isoprenylcysteine carboxylmethyltransferase (ICMT) with IC50 of 0.5 uM.
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ICMT inhibitor C75 is a potent, specific and cell-permeable inhibitor of the isoprenylcysteine carboxylmethyltransferase (ICMT) with IC50 of 0.5 uM.
C75 delays senescence and stimulates proliferation of late-passage HGPS cells and Zmpste24-deficient mouse fibroblasts.
| M.Wt | 367.533 | |
| Formula | C24H33NO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Judd WR, et al. Journal of Medicinal Chemistry. 2011;54:5031–5047.
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