IDE activator Ia1 | IDE activator | Probechem Biochemicals

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Chemical Structure : IDE activator Ia1

IDE activator Ia1 (LDN-1487, IDE activator 1)

Catalog No.: PC-26434Not For Human Use, Lab Use Only.

IDE activator Ia1 (IDE activator 1) is a potent, selective activator of insulin degrading enzyme (IDE), activates the hydrolysis of SP1 and FRET1 by IDE to ∼200% and ∼500%, activates the degradation of Aβ by ∼700%.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	398.26
Formula	C16H13Cl2N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(4-chlorophenyl)-2,6-dioxocyclohexane-1-carbaldehyde O-((5-chloro-1,2,3-thiadiazol-4-yl)methyl) oxime

References

1. Christelle Cabrol, et al. PLoS One. 2009;4(4):e5274.

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IDE activator Ia1 (LDN-1487, IDE activator 1)

Biological Activity

Physicochemical Properties

References

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