Chemical Structure : IKK16
CAS No.:
1186195-62-9
IKK16
(IKK 16)
Catalog No. : PC-63330Not For Human Use, Lab Use Only.
IKK16 is a potent, selective inhibitor of IκB kinase (IKK) with IC50 of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6333001
Biological Activity
IKK16 is a potent, selective inhibitor of IκB kinase (IKK ) with IC50 of 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively.
Physicochemical Properties
M.Wt
535.107
Formula
C28H31ClN6OS
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-(4-Pyrrolidin-1-yl-piperidin-1-yl)-[4-(4-benzo[b]thiophen-2-yl-pyrimidin-2-ylamino)phenyl]carboxamide hydrochloride
References
1. Waelchli R, et al. Bioorg Med Chem Lett.
2. Thein S, et al. Biochem Biophys Res Commun
3. Sordi R, et al. Mol Med.
4. Liu JC, et al. Cell Rep
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