Catalog No.: PC-35929Not For Human Use, Lab Use Only.
IM176OUT05 is a novel, and safe small molecule that improves the acquisition and maintenance of stem cell pluripotency, inhibits electron transport chain (ETC) in the A549 lung carcinoma cell line with IC50 of 3.2 uM, a mitochondrial OXPHOS inhibitor.
IM176OUT05 is a novel, and safe small molecule that improves the acquisition and maintenance of stem cell pluripotency, inhibits electron transport chain (ETC) in the A549 lung carcinoma cell line with IC50 of 3.2 uM, a mitochondrial OXPHOS inhibitor.
IM176OUT05 inhibits mitochondrial OXPHOS and increases lactate production by inducing the expression of glycolysis- and pluripotency-related genes.
IM176OUT05 facilitates the cycle of hair follicle regeneration in mice, stimulates the expression of stem cell metabolism-related and hair follicle regeneration-related genes during the early phases of hair regrowth.
Physicochemical Properties
M.Wt
255.75
Formula
C11H18ClN5
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
N-1-(2-methyl) phenethyl biguanide hydrochloride
References
1. Son MJ, et al. Exp Mol Med. 2018 Dec 6;50(12):160.
