Chemical Structure : IM176OUT05
CAS No.:
1643659-96-4
IM176OUT05
Catalog No.: PC-35929Not For Human Use, Lab Use Only.
IM176OUT05 is a novel, and safe small molecule that improves the acquisition and maintenance of stem cell pluripotency, inhibits electron transport chain (ETC) in the A549 lung carcinoma cell line with IC50 of 3.2 uM.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
IM176OUT05 is a novel, and safe small molecule that improves the acquisition and maintenance of stem cell pluripotency, inhibits electron transport chain (ETC) in the A549 lung carcinoma cell line with IC50 of 3.2 uM; inhibits mitochondrial OXPHOS and increases lactate production by inducing the expression of glycolysis- and pluripotency-related genes; facilitates the cycle of hair follicle regeneration in mice, stimulates the expression of stem cell metabolism-related and hair follicle regeneration-related genes during the early phases of hair regrowth.
Physicochemical Properties
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M.Wt
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255.75
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Formula
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C11H18ClN5
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20 °C 12 Months; 4°C 6 Months
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- In Solvent
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-80 °C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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N-1-(2-methyl) phenethyl biguanide hydrochloride
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References
1. Son MJ, et al. Exp Mol Med. 2018 Dec 6;50(12):160.
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