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Chemical Structure : IMP-1002
Catalog No.: PC-21135Not For Human Use, Lab Use Only.
IMP-1002 (IMP1002) is a potent P. falciparum N-myristoyltransferase (PfNMT) inhibitor, potently inhibits parasite growth with EC50 of 34 nM (3D7 strain).
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IMP-1002 (IMP1002) is a potent P. falciparum N-myristoyltransferase (PfNMT) inhibitor, potently inhibits parasite growth with EC50 of 34 nM (3D7 strain).
IMP-1002 can also overcome G386E-mediated resistance.
IMP-1002 is 4-fold more potent in killing parasites than the most potent previously reported PfNMT inhibitor DDD85646 (Cat# PC-62880).
| M.Wt | 435.55 | |
| Formula | C25H30FN5O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Schlott AC, et al. Cell Chem Biol. 2019 Jul 18;26(7):991-1000.e7.
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