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Chemical Structure : IMP-2373
Catalog No.: PC-21498Not For Human Use, Lab Use Only.
IMP-2373 is a highly targeted cyanopyrrolidine (CNPy) probe for pan-DUB to monitor DUB activity in physiologically relevant live cells.
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IMP-2373 is a highly targeted cyanopyrrolidine (CNPy) probe for pan-DUB to monitor DUB activity in physiologically relevant live cells.
IMP-2373 is a potent broad-spectrum DUB enzyme inhibitor with minimal off-target cytotoxicity.
IMP-2373 act as a competitive probe for in-cell target engagement by selective DUB inhibitors.
IMP-2373 is a powerful and useful application of activity-based probe (ABP) in drug discovery and development.
| M.Wt | 360.42 | |
| Formula | C21H20N4O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Daniel Conole, et al. Angew Chem Int Ed Engl. 2023 Nov 20;62(47):e202311190.
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