INCB106385 | Adenosine A2A/A2B receptor antagonist

Chemical Structure : INCB106385

Catalog No.: PC-26915Not For Human Use, Lab Use Only.

INCB106385 is a potent, selective dual A2A/A2B adenosine receptor antagonist.

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Biological Activity

INCB106385 is a potent, selective dual A2A/A2B adenosine receptor antagonist.

M.Wt	435.45
Formula	C23H17N9O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(8-amino-5-(1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)-2-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrazin-6-yl)benzonitrile

1. Chao Qi, et al. J Med Chem. 2026 May 27. doi: 10.1021/acs.jmedchem.6c00964.