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IPG7236

Chemical Structure : IPG7236

CAS No.: 2756350-91-9

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IPG7236 (IPG-7236, IPG 7236)

Catalog No.: PC-20372Not For Human Use, Lab Use Only.

IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM.

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5 mg $288 In stock
10 mg $458 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

IPG7236 (IPG 7236) is a potent and selective CCR8 antagonist with chemotaxis IC50 of 33.8 nM.
IPG7236 demonstrated an anti-cancer effect via modulating Treg and cytotoxic T (CD8+ T) cells.
IPG7236 alone or in combination with PD-1 antibody exhibited significant tumor suppression effects in the mouse xenograft model of human breast cancer.

Physicochemical Properties

M.Wt 429.58
Formula C23H31N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-2-methyl-N-(2-methyl-4-(N-(1-(1-methylpiperidin-4-yl)ethyl)sulfamoyl)phenyl)benzamide

References

1. Yong Wu, et al. J Med Chem. 2023 Mar 29. doi: 10.1021/acs.jmedchem.3c00030.

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