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IPL-576092

Chemical Structure : IPL-576092

CAS No.: 202415-99-4

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IPL-576092 (HMR-4011A;HMR 4011A;IPL576092;IPL 576092)

Catalog No.: PC-60531Not For Human Use, Lab Use Only.

A novel orally active, anti-inflammatory compound that inhibits leukocyte infiltration and changes in lung function in response to allergen challenge.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A novel orally active, anti-inflammatory compound that inhibits leukocyte infiltration and changes in lung function in response to allergen challenge; significantly attenuates characteristics of asthmatic response.

Asthma

Phase 2 Discontinued

Physicochemical Properties

M.Wt 334.5
Formula C21H34O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3S,5S,6R,7R,8R,9S,10R,13S,14S,17E)-17-ethylidene-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,6,7-triol

References

1. Kasserra CE, et al. Pulm Pharmacol Ther. 2004;17(5):309-18.

2. Shen Y, et al. J Org Chem. 2002 May 31;67(11):3908-10.

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