IRX4647 | RARγ agonist | Probechem Biochemicals

Chemical Structure : IRX4647

IRX4647 (IRX-4647, IRX 4647)

Catalog No.: PC-21164Not For Human Use, Lab Use Only.

IRX4647 is a selective RARγ agonist, regulates T cell biology and reduces syngeneic tumor growth of immune checkpoint-resistant lung cancer cell line (344SQ) when combined with anti-PD-L1.

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Biological Activity

IRX4647 is a selective RARγ agonist, regulates T cell biology and reduces syngeneic tumor growth of immune checkpoint-resistant lung cancer cell line (344SQ) when combined with anti-PD-L1.

Physicochemical Properties

M.Wt	379.50
Formula	C24H29NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-4-(3-(hydroxyimino)-3-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)propyl)benzoic acid

References

1. Wei CH, et al. Sci Rep. 2023 Sep 9;13(1):14907.

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IRX4647 (IRX-4647, IRX 4647)

Biological Activity

Physicochemical Properties

References

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