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ISM061-022

Chemical Structure : ISM061-022

CAS No.:

ISM061-022

Catalog No.: PC-23931Not For Human Use, Lab Use Only.

ISM061-018-2 is a potential pan-Ras inhibitor with IC50 values in the micromolar range, shows selectivity toward certain KRAS mutants.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

ISM061-018-2 is a potential pan-Ras inhibitor with IC50 values in the micromolar range, shows selectivity toward certain KRAS mutants.

Physicochemical Properties

M.Wt 344.42
Formula C21H20N4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(2-methoxy-3-methylphenyl)pyrimidin-4-yl)-1-methyl-1H-indol-4-amine

References

1. Ghazi Vakili M, et al. Nat Biotechnol. 2025 Jan 22. doi: 10.1038/s41587-024-02526-3.

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