ITH15004 | P2X7 antagonist | Probechem Biochemicals

Chemical Structure : ITH15004

Catalog No.: PC-24034Not For Human Use, Lab Use Only.

ITH15004 is potent, selective, and BBB-permeable antagonist of ATP-gated P2X7 purinergic receptor (P2X7) with IC50 of 9 uM.

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Biological Activity

ITH15004 is potent, selective, and BBB-permeable antagonist of ATP-gated P2X7 purinergic receptor (P2X7) with IC50 of 9 uM.

M.Wt	341.58
Formula	C13H7Cl3N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(6-chloro-9H-purin-9-yl)-1-(2,4-dichlorophenyl)ethan-1-one

1. Calzaferri F, et al. J Med Chem. 2021 Feb 25;64(4):2272-2290.