Chemical Structure : Icilin
CAS No.:
36945-98-9
Icilin
(AG 3-5;AG-3-5)
Catalog No. : PC-42799Not For Human Use, Lab Use Only.
Icilin (AG-3-5) is asuper-cooling agent that fuctions as a potent TRPM8 agonist with EC50 of 0.2 uM.
Packing Price Stock Quantity 5 mg (Free Sample) $18 In stock 0 1 2 3 4 5 10 mg $78 In stock 0 1 2 3 4 5 25 mg $128 In stock 0 1 2 3 4 5 50 mg Get quote 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4279901
Biological Activity
Icilin (AG-3-5) is asuper-cooling agent that fuctions as a potent TRPM8 agonist with EC50 of 0.2 uM.
Physicochemical Properties
M.Wt
311.2921
Formula
C16H13N3O4
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 54 mg/mL
Chemical Name/SMILES
2(1H)-Pyrimidinone, 3,6-dihydro-1-(2-hydroxyphenyl)-4-(3-nitrophenyl)-
References
1. Andersson DA, et al. J Neurosci. 2004 Jun 9;24(23):5364-9.
2. Behrendt HJ, et al. Br J Pharmacol. 2004 Feb;141(4):737-45.
3. McKemy DD, Nature. 2002 Mar 7;416(6876):52-8.et al.
4. Chuang HH, et al. Neuron. 2004 Sep 16;43(6):859-69.
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