Catalog No.: PC-61657Not For Human Use, Lab Use Only.
Imipramine Blue is a potent STAT5 inhibitor with a dual mechanism of action, potently inhibits STAT5 through liberation of endogenous phosphatase activity following NADPH oxidase (NOX) inhibition at 200-300 nM.
Imipramine Blue is a potent STAT5 inhibitor with a dual mechanism of action, potently inhibits STAT5 through liberation of endogenous phosphatase activity following NADPH oxidase (NOX) inhibition at 200-300 nM.
Imipramine Blue effectively kills mutant FLT3-driven AML cells through a similar mechanism as thapsigargin (TG), involving increased cytosolic calcium, at 75-150 nM.
Imipramine Blue is a novel anti-invasive small molecule that inhibits invasion of glioma in vitro.
