Imiquimod (R837) | TLR7 agonist | Probechem Biochemicals

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Chemical Structure : Imiquimod

CAS No.: 99011-02-6

Imiquimod (R837, S-26308)

Catalog No.: PC-20234Not For Human Use, Lab Use Only.

Imiquimod (Aldara,R-837,S-26308) is a small molecule TLR7 agonist, activates toll-like receptor 7 (EC50=2.1 μM) on immune cells and also enables an OGF-mediated block of cell proliferation (IC50=2 uM).

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100 mg	$38	In stock
500 mg	$88	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Imiquimod (Aldara,R-837,S-26308) is a small molecule TLR7 agonist, activates toll-like receptor 7 (EC50=2.1 μM) on immune cells and also enables an OGF-mediated block of cell proliferation (IC50=2 uM).

Physicochemical Properties

M.Wt	240.31
Formula	C14H16N4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine

References

1. Sidky YA,, et al. Cancer Res. 1992 Jul 1;52(13):3528-33.

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Imiquimod (R837, S-26308)

Biological Activity

Physicochemical Properties

References

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