Catalog No.: PC-45592Not For Human Use, Lab Use Only.
Indiplon (NBI-34060) is a potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively).
Indiplon (NBI-34060) is a potent GABAA receptor positive allosteric modulator that acts at the benzodiazepine site (Ki values are 1.2 and 1.7 nM in rat frontal cortex and cerebellum respectively).
Indiplon potentiates the GABA-activated chloride current in recombinant GABA(A) receptors in a dose-dependent and reversible manner in 293 cells, 10-fold selective for α1 subunit-containing receptors over GABA(A) receptors containing α2, α3, or α5 subunits.
