Ionomycin |CAS:56092-81-0 Probechem Biochemicals

Chemical Structure : Ionomycin

CAS No.: 56092-81-0

Ionomycin (SQ23377)

Catalog No.: PC-62654Not For Human Use, Lab Use Only.

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Biological Activity

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes.
Ionomycin also used to stimulate the intracellular production of the following cytokines; interferon, perforin, IL-2, and IL-4 - usually in conjunction with PMA.

Physicochemical Properties

M.Wt	709
Formula	C41H72O9
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	10,16-Docosadienoic acid, 11,19,21-trihydroxy-4,6,8,12,14,18,20-heptamethyl-22-[octahydro-5'-(1-hydroxyethyl)-2,5'-dimethyl[2,2'-bifuran]-5-yl]-9-oxo-, [2S-[2a[2'S,5'R(S)],5b(4S,6R,8R,10Z,12S,14S,16E,18S,19S,20R,21R)]]-

References

1. Gibbons E, et al. Biochim Biophys Acta. 2014 Oct;1838(10):2607-14.

2. Wang Y, et al. Ann Hematol. 2014 May;93(5):735-46.

3. Han S, et al. PLoS One. 2013 Oct 9;8(10):e76717.

Ionomycin (SQ23377)

Biological Activity

Physicochemical Properties

References

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