Ionomycin calcium salt |CAS:56092-82-1 Probechem Biochemicals

Chemical Structure : Ionomycin calcium salt

CAS No.: 56092-82-1

Ionomycin calcium salt

Catalog No.: PC-62653Not For Human Use, Lab Use Only.

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Biological Activity

Ionomycin is an ionophore produced by the bacterium Streptomyces conglobatus, used in research to raise the intracellular level of calcium (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes; also used to stimulate the intracellular production of the following cytokines; interferon, perforin, IL-2, and IL-4 - usually in conjunction with PMA.

Physicochemical Properties

M.Wt	747.07
Formula	C41H70CaO9
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-trihydroxy-22-((2S,5S)-5'-(1-hydroxyethyl)-2,5'-dimethyloctahydro-[2,2'-bifuran]-5-yl)-4,6,8,12,14,18,20-heptamethyl-9-oxodocosa-10,16-dienoic acid, calcium salt

References

1. Gibbons E, et al. Biochim Biophys Acta. 2014 Oct;1838(10):2607-14.

2. Wang Y, et al. Ann Hematol. 2014 May;93(5):735-46.

3. Han S, et al. PLoS One. 2013 Oct 9;8(10):e76717.