Catalog No.: PC-28614Not For Human Use, Lab Use Only.
Iopanoic acid (IOP) is a potent inhibitor of type I and type II 5'-deiodinase (DIO1 and DIO2), produces rapid, reversible suppression of peripheral thyroxine (T4) to T3 conversion, alongside comparative rescue strategies including Lugol's iodine, perchlorate, lithium, cholestyramine.
Iopanoic acid (IOP) is a potent inhibitor of type I and type II 5'-deiodinase (DIO1 and DIO2), produces rapid, reversible suppression of peripheral thyroxine (T4) to T3 conversion, alongside comparative rescue strategies including Lugol's iodine, perchlorate, lithium, cholestyramine.
Physicochemical Properties
M.Wt
570.94
Formula
C11H12I3NO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-(3-Amino-2,4,6-triiodobenzyl)butanoic acid
References
1. Renko K, et al. Thyroid. 2015 Aug;25(8):962-8.
2. Taylor P, et al. J Clin Endocrinol Metab. 2026 Oct 14:dgag421.
3. Newman C, et al. Eur Thyroid J. 2026 Mar 18;15(2):ETJ250350.
