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Chemical Structure : Ischemin
Catalog No.: PC-60199Not For Human Use, Lab Use Only.
Ischemin is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
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Ischemin is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
Ischemin inhibits the acetyl-lysine binding activity of CBP, inhibits p53 interaction with CBP and decreases p53 transcriptional activity.
Ischemin protects against doxorubicin-induced apoptosis in cardiomyocytes in vitro.
| M.Wt | 335.378 | |
| Formula | C15H17N3O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Borah JC, et al. Chem Biol. 2011 Apr 22;18(4):531-41.
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