Ischemin sodium

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Chemical Structure : Ischemin sodium

CAS No.: N/A

Catalog No.: PC-60198Not For Human Use, Lab Use Only.

Ischemin sodium is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.

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Biological Activity

Ischemin sodium is a cell permeable CBP bromodomain inhibitor with Kd of 19 uM.
Ischemin sodium inhibits the acetyl-lysine binding activity of CBP, inhibits p53 interaction with CBP and decreases p53 transcriptional activity.
Ischemin sodium protects against doxorubicin-induced apoptosis in cardiomyocytes in vitro.

Physicochemical Properties

M.Wt	357.36
Formula	C15H16N3O4SNa
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt

References

1. Borah JC, et al. Chem Biol. 2011 Apr 22;18(4):531-41.

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Ischemin sodium

Biological Activity

Physicochemical Properties

References

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