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Isoliquiritigenin

Chemical Structure : Isoliquiritigenin

CAS No.: 961-29-5

Isoliquiritigenin (Isoliquiritigen, SJ000286237)

Catalog No.: PC-28397Not For Human Use, Lab Use Only.

Isoliquiritigenin is a natural flavonoid that exhibits anti-inflammatory, anti-tumor and antioxidant activities, inhibits aldose reductase with an IC50 of 320 nM, is also a potent inhibitor of influenza virus replication with EC50 of 24.7 uM, also targets METTL3 with anti-leukemic effect.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Isoliquiritigenin is a natural flavonoid that exhibits anti-inflammatory, anti-tumor and antioxidant activities, inhibits aldose reductase with an IC50 of 320 nM, is also a potent inhibitor of influenza virus replication with EC50 of 24.7 uM, also targets METTL3 with anti-leukemic effect.

Physicochemical Properties

M.Wt 256.26
Formula C15H12O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one

References

1. Chen X, et al. J Mol Med (Berl). 2012 Nov;90(11):1311-9.

2. Aida K, et al. Planta Med. 1990 Jun;56(3):254-8.

3. Jiao CQ, et al. Cell Death Dis. 2025 Apr 1;16(1):233.

4. Traboulsi H, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):6317-27.

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