Catalog No.: PC-24812Not For Human Use, Lab Use Only.
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent, is a specific inhibitor ofimportin α/β-mediated nuclear import with potent antiviral activity towards both HIV-1 and DENV, also is a positive allosteric effector of P2X4 and α7 neuronal nicotinic acetylcholine receptor (nAChRs), also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import.
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent, is a specific inhibitor ofimportin α/β-mediated nuclear import with potent antiviral activity towards both HIV-1 and DENV, also is a positive allosteric effector of P2X4 and α7 neuronal nicotinic acetylcholine receptor (nAChRs), also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import.
Physicochemical Properties
M.Wt
875.09
Formula
C48H74O14
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
References
1. Khakh BS, et al. J Neurosci. 1999 Sep 1;19(17):7289-99.
2. Wagstaff KM, et al. Biochem J. 2012 May 1;443(3):851-6.
3. Raza S, et al. Microorganisms. 2020 Mar 13;8(3). pii: E409.
