JAB-3068 | SHP2 inhibitor | Probechem Biochemicals

Chemical Structure : JAB-3068

CAS No.: 2169223-48-5

Catalog No.: PC-20250Not For Human Use, Lab Use Only.

JAB-3068 (JAB3068) is a potent, selective and orally bioavailable allosteric inhibitor of SHP2 with IC50 of 25.8 nM.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$368	In stock
100 mg	$558	In stock
250 mg		Get quote

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Biological Activity

JAB-3068 (JAB3068) is a potent, selective and orally bioavailable allosteric inhibitor of SHP2 with IC50 of 25.8 nM.

M.Wt	476.54
Formula	C22H26F2N6O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-[4-[[3-Amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]ethanone

1. Patent WO2022135346 A1.