Chemical Structure : JAK-IN-21
CAS No.: 2445499-20-5
Catalog No.: PC-49377Not For Human Use, Lab Use Only.
JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.
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JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.
M.Wt | 372.392 | |
Formula | C19H16N8O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(Cyanomethyl)-4-[2-[[1-(cyanomethyl)-1H-pyrazol-4-yl]amino]-5-methyl-4-pyrimidinyl]benzamide |
1. Patent WO2020119819.
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