JAK-IN-21

Chemical Structure : JAK-IN-21

CAS No.: 2445499-20-5

Catalog No.: PC-49377Not For Human Use, Lab Use Only.

JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.

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Biological Activity

JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.

M.Wt	372.392
Formula	C19H16N8O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(Cyanomethyl)-4-[2-[[1-(cyanomethyl)-1H-pyrazol-4-yl]amino]-5-methyl-4-pyrimidinyl]benzamide

1. Patent WO2020119819.