You are here:Home-Chemical Inhibitors & Agonists-JAK/STAT Signaling-JAK-JAK-IN-21
JAK-IN-21

Chemical Structure : JAK-IN-21

CAS No.: 2445499-20-5

JAK-IN-21

Catalog No.: PC-49377Not For Human Use, Lab Use Only.

JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.

Packing Price Stock Quantity
5 mg $398 In stock
10 mg $598 In stock
25 mg $988 In stock
100 mg Get quote
1 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JAK-IN-21 is a selective and potent JAK inhibitor with IC50 of 1.73, 2.04, 109 and 62.9 nM against JAK1, JAK2, J2V617F and TYK2, respectively.

Physicochemical Properties

M.Wt 372.392
Formula C19H16N8O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(Cyanomethyl)-4-[2-[[1-(cyanomethyl)-1H-pyrazol-4-yl]amino]-5-methyl-4-pyrimidinyl]benzamide

References

1. Patent WO2020119819.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: