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Chemical Structure : JAK3-IN-1
CAS No.: 1805787-93-2
Catalog No.: PC-45647Not For Human Use, Lab Use Only.
JAK3-IN-1 is a potent and selective JAK3 inhibitor with IC50 of 4.8 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $400 | In stock | |
| 50 mg | $1200 | In stock | |
| 100 mg | $1680 | In stock |
Bulk size, bulk discount!
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JAK3-IN-1 is a potent and selective JAK3 inhibitor with IC50 of 4.8 nM; displays >150 fold selectivity versus JAK1 and JAK2; exhibits decent pharmacokinetic properties and is suitable for use in vivo.
| M.Wt | 508.0151 | |
| Formula | C26H30ClN7O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 47 mg/mL |
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| Chemical Name/SMILES |
2-Propenamide, N-[3-[[[5-chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]methyl]phenyl]- |
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1. Tan L, et al. J Med Chem. 2015 Aug 27;58(16):6589-606.
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