JCP174 | TgPPT1 inhibitor | Probechem Biochemicals

Chemical Structure : JCP174

JCP174 (JCP-174)

Catalog No.: PC-23296Not For Human Use, Lab Use Only.

JCP174 is a small molecule inhibitor of Toxoplasma gondii palmitoyl-protein thioesterase-1 (TgPPT1), enhances Toxoplasma host-cell invasion, triggers secretion of invasion-associated organelles, increases motility and enhances the invasive capacity of tachyzoites.

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Biological Activity

Physicochemical Properties

M.Wt	253.68
Formula	C12H12ClNO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	7-Amino-4-chloro-3-propoxy-isochromen-1-one

References

1. Child MA, et al. Nat Chem Biol. 2013 Oct;9(10):651-6.

2. Powers JC, et al. Biochemistry. 1990 Mar 27;29(12):3108-18.

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JCP174 (JCP-174)

Biological Activity

Physicochemical Properties

References

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