JF-NP-26

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Chemical Structure : JF-NP-26

Catalog No.: PC-27664Not For Human Use, Lab Use Only.

JF-NP-26 is a selecitve, photoactive mGlu5 receptor negative allosteric modulator (NAM), elicits with light pulses in the visible spectrum (405 nm), induces light-dependent analgesia in models of inflammatory and neuropathic pain in freely behaving animals.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	513.57
Formula	C30H28FN3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(7-(diethylamino)-2-oxo-2H-chromen-4-yl)methyl (2-((3-fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-yl)carbamate

References

1. Font J, et al. Elife. 2017 Apr 11;6:e23545.

2. Mastroiacovo F, et al. Stroke. 2026 May;57(5):1349-1361.

3. López-Cano M, et al. Methods Mol Biol. 2019;1947:351-359.

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JF-NP-26

Biological Activity

Physicochemical Properties

References

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