JMJD1C inhibitor 193D7 | JMJD1C inhibitor

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Chemical Structure : JMJD1C inhibitor 193D7

JMJD1C inhibitor 193D7 (193D7)

Catalog No.: PC-21777Not For Human Use, Lab Use Only.

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

Physicochemical Properties

M.Wt	317.36
Formula	C16H15NO4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(8-benzoyl-5-oxo-2,3,6,7-tetrahydro-5H-thiazolo[3,2-a]pyridin-6-yl)acetic acid

References

1. Long X, et al. Nat Immunol. 2024 Feb 14. doi: 10.1038/s41590-024-01746-8.

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JMJD1C inhibitor 193D7 (193D7)

Biological Activity

Physicochemical Properties

References

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