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JMJD1C inhibitor 193D7

Chemical Structure : JMJD1C inhibitor 193D7

CAS No.: 861224-48-8

JMJD1C inhibitor 193D7 (193D7)

Catalog No.: PC-21777Not For Human Use, Lab Use Only.

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

193D7 is a specific and oral inhibitor of histone demethylase JMJD1C with IC50 of 0.59 uM in in vitro demethylation assays, suppresses tumor growth by targeting intratumoral Treg cells.

Physicochemical Properties

M.Wt 317.36
Formula C16H15NO4S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(8-benzoyl-5-oxo-2,3,6,7-tetrahydro-5H-thiazolo[3,2-a]pyridin-6-yl)acetic acid

References

1. Long X, et al. Nat Immunol. 2024 Feb 14. doi: 10.1038/s41590-024-01746-8.

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