Chemical Structure : JNJ-1289
CAS No.: 792898-18-1
Catalog No.: PC-49232Not For Human Use, Lab Use Only.
JNJ-1289 (JNJ1289) is a potent, highly selective allosteric inhibitor of human spermine oxidase (hSMOX) with IC50 of 50 nM, inactive against hPAOX and LSD1 (IC50>2,000 nM).
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JNJ-1289 (JNJ1289) is a potent, highly selective allosteric inhibitor of human spermine oxidase (hSMOX) with IC50 of 50 nM, inactive against hPAOX and LSD1 (IC50>2,000 nM).
M.Wt | 308.359 | |
Formula | C16H12N4OS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-((4-imidazo[1,2,a]pyridine-3-ylthiazol-2-yl)amino)phenol |
1. Elsie Diaz, et al. Commun Biol. 2022 Aug 5;5(1):787.
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