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JNJ-1289

Chemical Structure : JNJ-1289

CAS No.: 792898-18-1

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JNJ-1289 (JNJ1289)

Catalog No.: PC-49232Not For Human Use, Lab Use Only.

JNJ-1289 (JNJ1289) is a potent, highly selective allosteric inhibitor of human spermine oxidase (hSMOX) with IC50 of 50 nM, inactive against hPAOX and LSD1 (IC50>2,000 nM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JNJ-1289 (JNJ1289) is a potent, highly selective allosteric inhibitor of human spermine oxidase (hSMOX) with IC50 of 50 nM, inactive against hPAOX and LSD1 (IC50>2,000 nM).

Physicochemical Properties

M.Wt 308.359
Formula C16H12N4OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((4-imidazo[1,2,a]pyridine-3-ylthiazol-2-yl)amino)phenol

References

1. Elsie Diaz, et al. Commun Biol. 2022 Aug 5;5(1):787.

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