JNJ-38893777 | TRPV1 inhibitor | Probechem Biochemicals

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Chemical Structure : JNJ-38893777

JNJ-38893777 (JNJ38893777)

Catalog No.: PC-63428Not For Human Use, Lab Use Only.

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JNJ-38893777 is a potent and selective transient receptor potential vanilloid 1 (TRPV1) channel antagonist for treatment of ociceptive and neuropathic pain.

Physicochemical Properties

M.Wt	536.526
Formula	C26H26F6N6
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(1-piperidinyl)-N-[4-(trifluoromethyl)phenyl]-7-[3-(trifluoromethyl)-2-pyridinyl]-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine

References

1. Manitpisitkul P, et al. Clin Drug Investig. 2015 Jun;35(6):353-63.

2. Meents JE, et al. J Headache Pain. 2015;16:57.

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JNJ-38893777 (JNJ38893777)

Biological Activity

Physicochemical Properties

References

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