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JNJ-42491293

Chemical Structure : JNJ-42491293

CAS No.: 1376334-37-0

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JNJ-42491293 (JNJ42491293)

Catalog No.: PC-20314Not For Human Use, Lab Use Only.

JNJ-42491293 (JNJ 42491293) is a potent, mGlu2-selective allosteric agonist and positive allosteric modulator (ago-PAM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    JNJ-42491293 (JNJ 42491293) is a potent, mGlu2-selective allosteric agonist and positive allosteric modulator (ago-PAM).

    Physicochemical Properties

    M.Wt 432.90
    Formula C22H23ClF2N4O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    8-chloro-3-(cyclopropylmethyl)-7-(4-(3,6-difluoro-2-methoxyphenyl)piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridine

    References

    1. Christian B M Poulie, et al. J Med Chem. 2020 Sep 10;63(17):9928-9949.

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