Chemical Structure : JNJ-9350
CAS No.: 326923-09-5
Catalog No.: PC-25675Not For Human Use, Lab Use Only.
JNJ-9350 is a potent, selective Spermine oxidase (SMOX) inhibitor with IC50 of 8 nM for human SMOX (hSMOX), shows remarkable selectivity over hPAOX (>89-fold).
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| 10 mg | $188 | In stock | |
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JNJ-9350 is a potent, selective Spermine oxidase (SMOX) inhibitor with IC50 of 8 nM for human SMOX (hSMOX), shows remarkable selectivity over hPAOX (>89-fold).
JNJ-9350 displays dose-response inhibition of hSMOX cellular activity with an IC50 value of 678 nM in A549 cells.
JNJ-9350 demonstrates stabilization of hSMOX with an IC50 of 2.3 μM in cellular hSMOX engagement assays.
| M.Wt | 422.49 | |
| Formula | C25H22N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-(3-(1H-imidazol-1-yl)propyl)-5,7-diphenylpyrazolo[1,5-a]pyrimidine-2-carboxamide |
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1. Llaveria J, et al. J Med Chem. 2025 Oct 27. doi: 10.1021/acs.jmedchem.5c01449.

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