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JNJ 39659100

Chemical Structure : JNJ 39659100

CAS No.: 24136-23-0

JNJ 39659100 (MBX-102, Arhalofenate)

Catalog No.: PC-49252Not For Human Use, Lab Use Only.

JNJ39659100 (MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

JNJ 39659100 (Arhalofenate, MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid.

Physicochemical Properties

M.Wt 415.793
Formula C19H17ClF3NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-acetamidoethyl (R)-2-(4-chlorophenyl)-2-(3-(trifluoromethyl)phenoxy)acetate

References

1. Gregoire FM, et al. Mol Endocrinol. 2009 Jul;23(7):975-88.

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