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JNJ 39659100

Chemical Structure : JNJ 39659100

CAS No.: 24136-23-0

JNJ 39659100 (MBX-102, Arhalofenate)

Catalog No.: PC-49252Not For Human Use, Lab Use Only.

JNJ39659100 (MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    JNJ 39659100 (MBX-102) is a nonthiazolidinedione (TZD) selective partial PPAR-γ agonist with insulin-sensitizing and glucose-lowering properties comparable to TZDs without dose-dependent increases in body weight, the prodrug ester of MBX-102 acid.

    Physicochemical Properties

    M.Wt 415.793
    Formula C19H17ClF3NO4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-acetamidoethyl (R)-2-(4-chlorophenyl)-2-(3-(trifluoromethyl)phenoxy)acetate

    References

    1. Gregoire FM, et al. Mol Endocrinol. 2009 Jul;23(7):975-88.

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