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JPC-3210

Chemical Structure : JPC-3210

CAS No.: 1609655-35-7

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JPC-3210 (JPC3210)

Catalog No.: PC-62611Not For Human Use, Lab Use Only.

JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    JPC-3210 is a potent antimalarial agent with IC50 of 2.5-19 nM, remains activity against multidrug-resistant Plasmodium falciparum lines with little cytotoxicity in mammalian cell lines.
    JPC-3210 exhibits longer plasma elimination half-life, and excellent in vivo efficacy against murine malaria.

    Physicochemical Properties

    M.Wt 398.446
    Formula C21H26F4N2O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-(tert-butyl)-2-((tert-butylamino)methyl)-6-(5-fluoro-6-(trifluoromethyl)pyridin-3-yl)phenol

    References

    1. Chavchich M, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3115-8.

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