JPE1375 | C5aR inhibitor | Probechem Biochemicals

Chemical Structure : JPE1375

CAS No.: 912344-10-6

Catalog No.: PC-72001Not For Human Use, Lab Use Only.

JPE1375 is a potent, peptidomimetic C5a receptor antagonist with IC50 of 39 nM, inhibits neutrophil influx in the RPAR in mice.

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Biological Activity

JPE1375 is a potent, peptidomimetic C5a receptor antagonist with IC50 of 39 nM.
JPE1375 inhibits neutrophil influx in the RPAR in mice.

M.Wt	955.102
Formula	C49H63FN10O9
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Hoo-Phe-Orn-Pro-hle-Pf-Phe-NH2

1. Schnatbaum K, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5088-92.