JXL020 | MPC inhibitor | Probechem Biochemicals

Chemical Structure : JXL020

Catalog No.: PC-27506Not For Human Use, Lab Use Only.

JXL020 is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 16.6 nM.

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Biological Activity

JXL020 is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 16.6 nM.

M.Wt	438.33
Formula	C21H12F6N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(1-(3,5-Bis(trifluoromethyl)benzyl)-1H-indol-3-yl)-2-cyanoacrylic acid

1. Xiaoguang Liu, et al. J Med Chem. 2021 Feb 25;64(4):2046-2063.