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JXL069

Chemical Structure : JXL069

CAS No.: 2260696-63-5

JXL069 (Suvomipic, JXL-069)

Catalog No.: PC-27505Not For Human Use, Lab Use Only.

Suvomipic (JXL069) is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 42.8 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Suvomipic (JXL069) is a potent, small molecule mitochondrial pyruvate carrier (MPC) inhibitor with IC50 of 42.8 nM.

Physicochemical Properties

M.Wt 439.32
Formula C20H11F6N3O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-(1-(3,5-Bis(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-cyanoacrylic acid

References

1. Xiaoguang Liu, et al. J Med Chem. 2021 Feb 25;64(4):2046-2063.

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